LEDGER SNIPPET
Ledger (181)
Knowledge Base (2)
Graph
REJECT
SYSTEM
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: during therapy exposure; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
C: 1.0000
S: 0.0005
RMS: 0.00106
3467fb816d2237e1b5da3590f01c7121fc8fd98a270862032830f1f474d5f06b
← prev:
c8498b5e7af965c6c6281382e2d1716e440bed423d57ca15d54e908f57bf120c
EXPERIMENT
SYSTEM
Turn 36
population_tracking: SUPPORTS
c8498b5e7af965c6c6281382e2d1716e440bed423d57ca15d54e908f57bf120c
← prev:
d68c78425d93a5b00b3217dae7d34c0abc87c2022caf10533840fd9469d85e05
REJECT
SYSTEM
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
C: 1.0000
S: 0.0006
RMS: 0.00103
7645feacc7a1bafe44c0cff6757dab598acb9b5eea6f702a7552b66e5e7eee2c
← prev:
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
REVISION
Agent A
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: during therapy exposure; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
d68c78425d93a5b00b3217dae7d34c0abc87c2022caf10533840fd9469d85e05
← prev:
9ed569a9c0da88c04850d96d0b096bcf81ef969d87b67e04493e6a21202520b3
GRAPH_UPDATE
SYSTEM
Turn 36
9ed569a9c0da88c04850d96d0b096bcf81ef969d87b67e04493e6a21202520b3
← prev:
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
EXPERIMENT
SYSTEM
Turn 36
marker_measurement: SUPPORTS
e2b1613b51ebf079c0f2b776aa63008cf342ac497faef023ce1008953a9e7adc
← prev:
a17a599d20f8e093f1e57ae0e05e12bf376cae451ca3959430a3d1fe1e503321
CRITIQUE
Agent B
Turn 36
"Mark uncertainty explicitly where evidence is indirect; tighten claims."
C: 0.9880
S: 0.0050
RMS: 0.00030
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
← prev:
e2b1613b51ebf079c0f2b776aa63008cf342ac497faef023ce1008953a9e7adc
PROPOSE
Agent A
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes.
a17a599d20f8e093f1e57ae0e05e12bf376cae451ca3959430a3d1fe1e503321
← prev:
d2d87191b6a189a65b85715f553dd783c29414a425cbe8f1c9ac73593fd2abb5
REVISION
Agent A
Turn 35
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
757fd2e57ab437664474516c75c8c5fd4aab1c54c4914e7031b7df4130854550
← prev:
ace278adf2c7753dbb4bb95063801a59d0a8607a47cef5091a3c421a1d45f480
CONSENSUS
SYSTEM
Turn 35
[Ref: 3b72feb3] Extending [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, we propose that temporal dynamics shift under varying microenvironmental conditions. Revised: under nutrient-SE44 Gate
C≥0.985
S≤0.01
RMS≤0.001
Speed (ms)
1500ms
Require Citations
Stability Threshold
1
Educational/Research Simulation Only.
Not medical advice. Not a clinical decision tool.
SE44 Diagnostics (Agent B)
Coherence
1.0000
Entropy
0.0005
RMS Drift
0.00106
Result:
REBIND → PROVISIONAL
Thresholds: C≥0.985, S≤0.01, RMS≤0.001
Consensus Timeline
immune evasion
KNOWN
2 turns
NaNs
695d79f9
Invalid Date
immune evasion
KNOWN
2 turns
NaNs
695d7a0c
Invalid Date
Ledger (181)
Knowledge Base (2)
Graph
REJECT
SYSTEM
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: during therapy exposure; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
C: 1.0000
S: 0.0005
RMS: 0.00106
3467fb816d2237e1b5da3590f01c7121fc8fd98a270862032830f1f474d5f06b
← prev:
c8498b5e7af965c6c6281382e2d1716e440bed423d57ca15d54e908f57bf120c
EXPERIMENT
SYSTEM
Turn 36
population_tracking: SUPPORTS
c8498b5e7af965c6c6281382e2d1716e440bed423d57ca15d54e908f57bf120c
← prev:
d68c78425d93a5b00b3217dae7d34c0abc87c2022caf10533840fd9469d85e05
REJECT
SYSTEM
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
C: 1.0000
S: 0.0006
RMS: 0.00103
7645feacc7a1bafe44c0cff6757dab598acb9b5eea6f702a7552b66e5e7eee2c
← prev:
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
REVISION
Agent A
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: during therapy exposure; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
d68c78425d93a5b00b3217dae7d34c0abc87c2022caf10533840fd9469d85e05
← prev:
9ed569a9c0da88c04850d96d0b096bcf81ef969d87b67e04493e6a21202520b3
GRAPH_UPDATE
SYSTEM
Turn 36
9ed569a9c0da88c04850d96d0b096bcf81ef969d87b67e04493e6a21202520b3
← prev:
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
EXPERIMENT
SYSTEM
Turn 36
marker_measurement: SUPPORTS
e2b1613b51ebf079c0f2b776aa63008cf342ac497faef023ce1008953a9e7adc
← prev:
a17a599d20f8e093f1e57ae0e05e12bf376cae451ca3959430a3d1fe1e503321
CRITIQUE
Agent B
Turn 36
"Mark uncertainty explicitly where evidence is indirect; tighten claims."
C: 0.9880
S: 0.0050
RMS: 0.00030
a35bc90868a2cc3e20e8b356e7641dc99d4978553788dc4f38b4018c2c042c51
← prev:
e2b1613b51ebf079c0f2b776aa63008cf342ac497faef023ce1008953a9e7adc
PROPOSE
Agent A
Turn 36
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes.
a17a599d20f8e093f1e57ae0e05e12bf376cae451ca3959430a3d1fe1e503321
← prev:
d2d87191b6a189a65b85715f553dd783c29414a425cbe8f1c9ac73593fd2abb5
REVISION
Agent A
Turn 35
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
757fd2e57ab437664474516c75c8c5fd4aab1c54c4914e7031b7df4130854550
← prev:
ace278adf2c7753dbb4bb95063801a59d0a8607a47cef5091a3c421a1d45f480
CONSENSUS
SYSTEM
Turn 35
[Ref: 3b72feb3] Extending [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, we propose that temporal dynamics shift under varying microenvironmental conditions. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
C: 0.9855
S: 0.0075
RMS: 0.00072
d2d87191b6a189a65b85715f553dd783c29414a425cbe8f1c9ac73593fd2abb5
← prev:
ace278adf2c7753dbb4bb95063801a59d0a8607a47cef5091a3c421a1d45f480
EXPERIMENT
SYSTEM
Turn 35
marker_measurement: INCONCLUSIVE
ace278adf2c7753dbb4bb95063801a59d0a8607a47cef5091a3c421a1d45f480
← prev:
79403d7474efd382dfcf4ec76342c5b7ce7286df1a4b5cebe2a1b80b4f880860
CRITIQUE
Agent B
Turn 35
"Topic-shift/drift check: ensure the claim stays within defined scope. Separate observed correlation from causal claim; propose discriminating tests."
C: 0.9910
S: 0.0050
RMS: 0.00030
0e5f7ab5cf19c8babdb9ef1de4eca27304a6559057c18edb13789adcb9125e14
← prev:
79403d7474efd382dfcf4ec76342c5b7ce7286df1a4b5cebe2a1b80b4f880860
REJECT
SYSTEM
Turn 35
[Ref: 3b72feb3] The interplay between [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity and environmental factors may create feedback loops that amplify or dampen the effect. Revised: within specific cell populations; predicts differential response across subclones. Building on prior work [3b72feb3].
C: 1.0000
S: 0.0006
RMS: 0.00104
79403d7474efd382dfcf4ec76342c5b7ce7286df1a4b5cebe2a1b80b4f880860
← prev:
d68f8d1f03d857925b33135daa3de2709942f9aa86fd21feebcfd8d68d292416
REVISION
Agent A
Turn 34
[Ref: 3b72feb3] Extending [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, we propose that temporal dynamics shift under varying microenvironmental conditions. Revised: under nutrient-limited conditions; predicts tradeoffs (growth vs. survival) depending on constraints. Building on prior work [3b72feb3].
92bc23e10ecdd75e3892c9decafa9c713f3bc03519a5cb53847b5659e0ef30d3
← prev:
f98aef2bf8a4769523fc937c4e19640fddc96c238d529d313bcbf6d9544a1cc3
PROPOSE
Agent A
Turn 35
[Ref: 3b72feb3] Refining [Bootstrap - No fossil reference] Suppressive myeloid populations can reduce effective anti-tumor immunity, cell-state transitions may explain context-dependent outcomes.
d68f8d1f03d857925b33135daa3de2709942f9aa86fd21feebcfd8d68d292416
← prev:
92bc23e10ecdd75e3892c9decafa9c713f3bc03519a5cb53847b5659e0ef30d3
EXPERIMENT
SYSTEM
Turn 34
co_culture_model: SUPPORTS
f98aef2bf8a4769523fc937c4e19640fddc96c238d529d313bcbf6d9544a1cc3
← prev:
c5cff0a9e4676e9e690acf44b2f0df3d183f4b79330b2962522e21a0a7beb4d6
CRITIQUE
Agent B
Turn 34
"Separate observed correlation from causal claim; propose discriminating tests."
C: 0.9910
S: 0.0050
RMS: 0.00030
c5cff0a9e4676e9e690acf44b2f0df3d183f4b79330b2962522e21a0a7beb4d6
← prev:
4605d24774d1aea97750480e9958e17426dc443259566dd2536388be8fdd7fbe
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